Back to news and publications

Strata Oncology Announces Addition of Gilead as Strata PATH Trial Collaborator

Gilead to supply TRODELVY for prospective, pan-tumor trial

January 18, 2023

January 18, 2023

Gilead to supply TRODELVY for prospective, pan-tumor trial

Strata Oncology, Inc. a next-generation precision oncology company enabling smarter and earlier cancer treatment, today announced that Gilead Sciences, Inc. has agreed to collaborate on the Strata Precision Indications for Approved THerapies (Strata PATHTM ) trial by providing TRODELVY® (Sacituzumab govitecan-hziy) for eligible patients with cancer. 

Strata PATH is a prospective pan-tumor therapeutic trial designed to evaluate the efficacy and safety of multiple FDA-approved cancer therapies in new, biomarker-guided patient populations. Several types of biomarkers are being evaluated, including quantitative RNA and multivariate algorithms that may optimize the use of different anti-cancer therapies. These biomarkers can be analyzed in parallel with the genomic mutations assessed by comprehensive genomic profiling (CGP), thus maximizing the information available from often limited tumor tissue samples.

“As the first diagnostics company to run its own prospective interventional trial to show the utility of its tests, Strata is honored to have the support and collaboration of forward-thinking biopharma companies like Gilead Sciences for the Strata PATH trial,” said Dan Rhodes, Ph.D., Chief Executive Officer and co-founder, Strata Oncology. “Quantitative RNA and multivariate biomarkers have the potential to optimize the use of expression-based therapies and improve the outcomes and the quality of life for cancer patients.”

Media Inquiries

Rachel Ford Hutman  rachel@fordhutmanmedia.com 301.801.5540

About Strata PATH

The Strata Precision Indications for Approved THerapies (Strata PATH) trial, is a 700-patient prospective pan-tumor therapeutic trial designed to evaluate the efficacy and safety of multiple FDA-approved cancer therapies in new, biomarker-guided patient populations. Strata PATH will enroll patients with advanced cancer, as well as patients with early-stage cancer who have evidence of micrometastatic disease after initial treatment. All therapies being evaluated in Strata PATH are FDA-approved in oncology with demonstrated safety profiles in the advanced setting. Enrollment for multiple arms in Stata PATH is based on novel quantitative RNA and multivariate algorithms Strata Oncology developed using its clinical molecular database comprising DNA mutation profiles and quantitative RNA expression data from tens of thousands of patients coupled with detailed treatment history and outcomes data. A range of therapeutic classes will be evaluated in Strata PATH including targeted therapies, antibody-drug conjugates, immunotherapies, and angiogenesis inhibitors.

In the news

The latest from Strata Oncology

December 1, 2023

Strata Oncology Announces Presentations on Proprietary Multivariate Biomarkers at North America Conference on Lung Cancer and San Antonio Breast Cancer Symposium

November 8, 2023

Strata Oncology Recognized as “Diagnostics Innovation Of The Year” by BioTech Breakthrough Awards

September 11, 2023

Dr. Nair on the clinical utility of Immunotherapy Response Score 

September 10, 2023

Immunotherapy Response Score (IRS) Predicts Pembrolizumab Clinical Benefit in Patients with NSCLC in TPS≥50%

September 7, 2023

Strata Oncology Announces New Data Supporting Utility of Immunotherapy Response Score to Guide First-Line Treatment Decisions in Non-small Cell Lung Cancer

July 10, 2023

Immunotherapy Response Score (IRS) Predicts Pembrolizumab Clinical Benefit in Patients with NSCLC in TPS≥50%

July 3, 2023

Validation of Immunotherapy Response Score as predictive of pan-solid tumor anti-PD-1/PD-L1 benefit

June 14, 2023

Dr Thomas on the Predictive Value of IRS For Pembrolizumab Benefit in Advanced Solid Tumors

June 1, 2023

Evaluation of Immunotherapy Response Score (IRS) for Predicting Pembrolizumab (pembro) Clinical Benefit in Patients (pts) with Advanced Solid Tumors

May 2, 2023

Strata Oncology Receives Honorable Mention in Fast Company’s 2023 World Changing Ideas Awards